2-C-Methylerythritol 4-phosphate
Names | |
---|---|
IUPAC name 2-C-Methyl-D-erythritol 4-(dihydrogen phosphate) | |
Systematic IUPAC name (2R,3S)-2,3,4-Trihydroxy-3-methylbutyl dihydrogen phosphate | |
Other names 2-C-Methylerythritol 4-phosphate Methyl-D-erythritol phosphate | |
Identifiers | |
CAS Number |
|
3D model (JSmol) |
|
Abbreviations | MEP |
ChEBI |
|
ChemSpider |
|
PubChem CID |
|
CompTox Dashboard (EPA) |
|
InChI
| |
| |
Properties | |
Chemical formula | C5H13O7P |
Molar mass | 216.126 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
2-C-Methyl-D-erythritol 4-phosphate (MEP) is an intermediate on the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis.[1] It is the first committed metabolite on that pathway on the route to IPP and DMAPP.
See also
- DXP reductoisomerase
- MEP pathway (formerly known as the non-mevalonate pathway)
- Fosmidomycin
References
- ^ Takahashi S, Kuzuyama T, Watanabe H, Seto H (1998). "A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 9879–84. Bibcode:1998PNAS...95.9879T. doi:10.1073/pnas.95.17.9879. PMC 21430. PMID 9707569.
External links
- 2-C-methylerythritol+4-phosphate at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- v
- t
- e
to HMG-CoA | |
---|---|
Ketone bodies | |
to DMAPP | |
Geranyl- | |
Carotenoid |
- Lanosterol
- 14-demethyllanosterol
- 4alpha-Methylzymosterol
- Zymosterone
- Zymosterol
- Zymosterol
- Zymostenol
- Lathosterol
- 7-Dehydrocholesterol
- Cholesterol
- Zymosterol
- Cholesta-7,24-dien-3-ol
- 7-Dehydrodesmosterol
- Desmosterol
- Cholesterol
to Steroid hormones
- 22R-Hydroxycholesterol
- 20α,22R-Dihydroxycholesterol
- See here instead.
To Sitosterol |
|
---|---|
To Ergocalciferol |
|
This biochemistry article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e