PTPN23 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3RAU, 5CRV, 5CRU |
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Identifiers |
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Aliases | PTPN23, HD-PTP, HDPTP, PTP-TD14, protein tyrosine phosphatase, non-receptor type 23, protein tyrosine phosphatase non-receptor type 23, NEDBASS |
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External IDs | OMIM: 606584; MGI: 2144837; HomoloGene: 135706; GeneCards: PTPN23; OMA:PTPN23 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3p21.31 | Start | 47,381,011 bp[1] |
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End | 47,413,435 bp[1] |
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Gene location (Mouse) |
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![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 F2 | Start | 110,214,150 bp[2] |
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End | 110,237,281 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- pituitary gland
- skin of arm
- anterior pituitary
- right hemisphere of cerebellum
- right lobe of thyroid gland
- stromal cell of endometrium
- left lobe of thyroid gland
- gastrocnemius muscle
- canal of the cervix
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| Top expressed in | - internal carotid artery
- ventricular zone
- external carotid artery
- yolk sac
- granulocyte
- neural layer of retina
- superior frontal gyrus
- tail of embryo
- primary visual cortex
- genital tubercle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/01/PBB_GE_PTPN23_gnf1h06048_at_fs.png/250px-PBB_GE_PTPN23_gnf1h06048_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - phosphoprotein phosphatase activity
- phosphatase activity
- protein binding
- protein tyrosine phosphatase activity
- protein kinase binding
- hydrolase activity
| Cellular component | - cytoplasm
- ciliary basal body
- endosome
- cell projection
- cilium
- nucleoplasm
- early endosome
- extracellular exosome
- cytoskeleton
- cytoplasmic vesicle
- nucleus
- nuclear body
- cytosol
| Biological process | - positive regulation of homophilic cell adhesion
- cilium assembly
- regulation of cell migration
- protein dephosphorylation
- positive regulation of adherens junction organization
- cell projection organization
- protein transport
- positive regulation of early endosome to late endosome transport
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
- negative regulation of epithelial cell migration
- dephosphorylation
- peptidyl-tyrosine dephosphorylation
- early endosome to late endosome transport
- positive regulation of Wnt protein secretion
- transport
- endocytic recycling
- cellular response to cytokine stimulus
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 47.38 – 47.41 Mb | Chr 9: 110.21 – 110.24 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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