KCNE1 |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | | |
Ідентифікатори |
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Символи | KCNE1, ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK, potassium voltage-gated channel subfamily E regulatory subunit 1 |
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Зовнішні ІД | OMIM: 176261 MGI: 96673 GeneCards: KCNE1 |
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Пов'язані генетичні захворювання |
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Jervell-Lange Nielsen syndrome, Romano–Ward syndrome[1] |
Онтологія гена |
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Молекулярна функція | • potassium channel activity • delayed rectifier potassium channel activity • voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization • voltage-gated ion channel activity • telethonin binding • potassium channel regulator activity • GO:0001948, GO:0016582 protein binding • voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization • voltage-gated potassium channel activity • transmembrane transporter binding |
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Клітинна компонента | • мембрана • integral component of membrane • voltage-gated potassium channel complex • клітинна мембрана • cell surface • Z discdkac • apical plasma membrane • membrane raft • лізосома |
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Біологічний процес | • regulation of ion transmembrane transport • protein O-linked glycosylation • ventricular cardiac muscle cell action potential • cardiac muscle cell action potential involved in contraction • ion transport • слух • potassium ion transport • membrane repolarization • negative regulation of protein targeting to membrane • membrane repolarization during action potential • regulation of delayed rectifier potassium channel activity • cardiac conduction • potassium ion transmembrane transport • positive regulation of potassium ion transmembrane transport • protein N-linked glycosylation • membrane repolarization during cardiac muscle cell action potential • regulation of heart rate by cardiac conduction • regulation of potassium ion transmembrane transport • negative regulation of delayed rectifier potassium channel activity • cellular response to cAMP • regulation of ventricular cardiac muscle cell membrane repolarization • membrane repolarization during ventricular cardiac muscle cell action potential • GO:0015915 транспорт • potassium ion export across plasma membrane |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | NM_000219 NM_001127668 NM_001127669 NM_001127670 NM_001270402
| NM_001270403 NM_001270404 NM_001270405 |
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RefSeq (білок) | NP_000210 NP_001121140 NP_001121141 NP_001121142 NP_001257331
| NP_001257332 NP_001257333 NP_001257334 NP_000210.2 |
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Локус (UCSC) | Хр. 21: 34.45 – 34.51 Mb | Хр. 16: 92.14 – 92.16 Mb |
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PubMed search | [2] | [3] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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